Guido van Rossum said in the latest FLOSS Weekly podcast:
My personal favorite -- and I expect that that will remain a personal favorite for a long time -- is something named Django. ... I highly recommend it.
has been my tool for a new project of mine, has been worth it the time spent learning Django
(right now my personal favourite programming language).
preferred setup is Apache
, this has make my choice easier because I've been always using Apache
If you want to give it a try(I recommend it), read the Part 1
of the tutorial.
And if you have doubts about performance, read this